Evolution in action: Lizards losing limbs Study: Some Australian skinks have gone legless in just 3.6 million years A Lerista skink, which has a snake-like body, at one time had five fingers. Evolution has resulted in a loss of the species' limbs. Mark Hutchinson LiveScience Obama Could Lift Stem Cell Funding Ban World Needs a Backup Plan The Obama Conspiracies: Truth Will Be Revealed 8 Ways to Green Your Yard What Happens if You Eat Dog Food? Related stories What's this? Supernatural science: Why we want to believe Video gamers are surprisingly fit, says study Understanding the power of music U.S. droughts can last for centuries Scientists grow bigger, better diamonds Most popular Most viewed Top rated Most e-mailed 2 Dutch men guilty of injecting 14 with HIV Austrian incest father charged with murder City Halls call out for help from Obama Prostitution Scandals of the Rich, Famous & Powerful Police: Fla. girl shot peer in crowded school hall Most viewed on msnbc.com By Robin Lloyd updated 2:23 p.m. ET Nov. 12, 2008 Some slender Australian lizards called skinks have gone from being five-fingered to legless (like most snakes) in just 3.6 million years, a new study finds. That's a blink of an eye in geologic time.
ScienceDaily (Oct. 2, 2008) -- MicroRNAs, the tiny molecules that fine-tune gene expression, were first discovered in 1993. But it turns out they've been around for a billion years.
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Evidence reported in Nature on October 1 by scientists in the lab of Whitehead Member and Howard Hughes Medical Institute investigator David Bartel provides a window into the early evolution of these key regulators, placing their origin within the earliest of animal lineages. The research also suggests that microRNAs present early on have undergone extensive changes, which likely have altered their functions across various lineages.
"This is the first evidence that microRNAs were present within the earliest animal lineages and are not just characteristic of more complex animals," says Andrew Grimson, a postdoctoral fellow in Bartel's lab. Scientists knew that microRNAs existed within bilaterians, an evolutionary group that includes everything from worms to fruit flies to humans, he explains. "Remarkably, we discovered their presence within sponge, a member of the earliest diverging group of animals."
The scientists used high-throughput sequencing to probe samples from animals that diverged before the origin of bilaterian animals. The sponge (Amphimedon queenslandica) represents a group of animals that split off in evolution very early, whereas the starlet sea anemone (Nematostella vectensis) split off more recently.